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Core/shell nonwovens in which enzyme is immobilized (Dr. Mizuno’s laboratory at Nagoya Institute of Technologies)


The hydrophilic copolymer of acrylamide (AM) and diacetone acrylamide (DAAM), poly(AM/DAAM),
was used as the base material to obtain the core unit of nanofibers. During electrospinning,
poly(AM/DAAM) was crosslinked with the bifunctional crosslinker adipic acid dihydrazide (ADH) in the presence of enzyme molecules.
The cores were wrapped with hydrophobic poly(ε-caprolactone) (PCL) layers as shell unit.
It has been introduced that core-shell fibermats were effective a as protein-releasing cell-incubation scaffolds.

*The abstract and articles were provided by Dr. Mizuno, Associate Professor. Thank you very much!

Our coaxial spinneret was used for spinning the core/shell nonwovens.

⇒BCSJ 2020

⇒CAPS 2020